Southampton have lost their first three matches on their return to the Premier League so they will be desperate to pick up at least a point against Manchester United on Saturday.
After defeats to Newcastle, Nottingham Forest and Brentford, Saints face a United side who were thumped 3-0 by Liverpool at Old Trafford before the international break.
That result increased the pressure on manager Erik ten Hag, whose squad remains depleted by injuries, and United have won only one of their last seven away matches in the top flight.
Team news
Southampton are expected to be missing injured goalkeeper Gavin Bazunu and striker Ross Stewart. Kamaldeen Sulemana (ankle) faces a fitness test.
United’s Bruno Fernandes suffered a knock in Portugal’s Nations League win over Scotland but should be fit to start.
However, Leny Yoro, Tyrell Malacia, Mason Mount, Rasmus Hojlund, Luke Shaw and Victor Lindelof remain sidelined for the Red Devils.
The stats
Southampton have lost two of their first three Premier League games by a 1-0 scoreline.
Saints’ only league goal this season was scored in the 95th minute.
Southampton’s home fixtures in last season’s Championship averaged 3.61 goals per game.
United have won only one of their last seven Premier League away fixtures.
The Red Devils have been losing at half-time and full-time in four of their last seven league matches.
Both teams have scored in only two of United’s last seven league games.